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Alzheimer's disease by excess protein? PDF Print E-mail
An international team of researchers analyzed the associations of diet with different types of Alzheimer's disease. Although primarily interested in the factors triggering the formation of amyloid plaques, accidentally discovered that a menu rich in fat leads to a reduction in brain size (Molecular Neurodegeneration).


Scientists from Canada, USA and Great Britain worked with transgenic mice, who had mutated form of human protein beta-amyloid precursor (APP? Amyloid precursor protein). Animals assigned to one of four dietary groups: 1) the ordinary food, 2) feed high-fat and low in carbohydrates, 3) high protein with low content of carbohydrates and 4) low fat with plenty of carbohydrates. Academics have looked at the importance of both brain and body, and the process of plaques and a few to areas of the brain, where damage is responsible for memory impairment of Alzheimer's disease. The researchers found that rodents with 3.grupy (high protein) have a brain about 5% lighter than the representatives of other groups, and hippocampal regions are less developed. The results were a big surprise, and although experts later conducted research for mice, is still not known whether weight loss is associated with brain . Nevertheless, on the basis of the literature on the subject, they risk a finding that a high protein diet because the neurons become more susceptible to the formation of plaques. This is even more reasonable to assume that mice eat a high fat had elevated levels of proteins, forming plaques, but was not seen in a similar range of their destruction. Professor Sam Gandy of Mount Sinai School of Medicine believes that in the future, make sure that a diet rich in proteins associated himself with neurotoxicity, especially in patients for the occurrence of critical or progress of neurodegenerative diseases.
 
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